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Precedex ®

Indications and Safety Information

Precedex is indicated for sedation in nonintubated patients prior to and during surgical and other procedures and in intubated and mechanically ventilated patients during treatment in an intensive care setting.

Precedex should be administered by continuous infusion not to exceed 24 hours.

Caution should be exercised when administering Precedex to patients with advanced heart block and/or severe ventricular dysfunction.

Clinically significant episodes of bradycardia, sinus arrest and hypotension have been associated with Precedex infusion and may necessitate medical intervention.

Please see a more complete description of these and other Warnings and Precautions in the full prescribing information.

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Resources & Tools

To download the PDF files below, click on the image. You must have the lastest version of Acrobat Reader. Click here to download.

Dosing Guidelines

A pocket-sized guide that summarizes recommended Precedex dosing for sedation in the intensive care setting and during surgical and other procedures.


ICU Sedation Dosing Card

A card summarizing recommended dosing for Precedex in an intensive care setting.


Procedural Sedation Dosing Card

A card summarizing recommended dosing for Precedex during surgical and other procedures.


MAC Protocol

An adult treatment protocol based on use of Precedex in a Phase III, randomized, multicenter, double-blind study of 326 patients undergoing monitored anesthesia care for orthopedic and other elective surgeries and procedures.


AFOI Protocol

An adult treatment protocol based on use of Precedex in a Phase III, randomized, multicenter, double-blind study of 105 patients with high-risk airways undergoing elective awake fiberoptic intubation.


Precedex Full Prescribing Information


What to expect with Precedex


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Presented by:

  • Christopher Young, MD, Chief of Critical Care Medicine (Department of Anesthesiology) at Duke University Medical Center in Durham, North Carolina.
  • Dan Herr, MD, an Intensivist at Washington Hospital Center in Washington, DC.

Dosing Calculator


To determine the Precedex infusion rate and total volume infused by patient weight, choose one of the interactive calculators below.

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